Liquid
Chromatography (LC) has indeed proved to be a boon for life sciences
industry and in particular pharmaceuticals. LC has the ability to
segregate a wide variety of chemical mixtures when compared to other
chromatography techniques. The market for LC around the world is
growing at a healthy rate. Let’s understand what this market and LC
process is all about.
What do we mean by Liquid
Chromatography?
Liquid chromatography is a separation
technique wherein a small amount of liquid sample is injected into a
tube that is packed with porous particles (which is often called as
the stationary phase). Next, the individual components of the sample
are transported along the packed tube (column) by a liquid moved by
gravity. Now the components are separated from one another by the
column packing that includes different chemical and/or physical
interactions between their molecules and the packing
particles.
Lastly, the segregated components are collected at
the exit of this column and identified by an external measurement
technique, such as a spectrophotometer that measures the intensity of
the color, or by another device that can measure their amount. Liquid
Chromatography is now come to known as Flash Chromatography. HPLC
(High Performance/Pressure Liquid Chromatography) is considered to be
the best LC technique because of the higher efficiency offered in
separating wide range of chemical blends.
Recent Trends and
Future of the Liquid Chromatography Market
With introduction
of latest technology, LC Market, too, has witnessed ground breaking
solutions in the form of introduction of new systems such as fast LC
and Ultra HPLC. Organizations are coming together to develop and
enhance the throughput and resolution by using smaller particle size
columns. It is due to this that the UHPLC systems are introduced
which has the remarkable capability to run at extremely high
temperatures. The demand for UHPLC instruments is also on the
rise.
Next, organizations are now introducing customized
systems that are meant for different industries. For instance, HPLC
is now used by clinical research organizations for genetic analysis,
veterinary sciences and even toxicology. However, with introduction
of improved systems often pose new challenges too. Companies are
merging to improve their products and services. Another trend
is that the providers of LC equipments are joining hands with
software companies for chemoinformatics.
Looking at the
activities going on in the LC Market, it is expected that the market
will grow to approx $4.7 billion by next year. Out of this US itself
will have a share of $1 billion. As the pressure on pharmaceutical
industries increases substantially to introduce new drugs in the
market, the market for LC instruments and equipments will see a
steady growth. The future seems to be bright for HPLC
parts
makers. Countries such as Japan, India and Puerto Rico will also see
manufactures coming and setting up production facilities due to the
low cost advantage.
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